I'm a 37 year young female whom inherited ADHD from my Dad and OCD from my Mom. The ADHD symptoms I have are typical: general underachievement and inability to complete projects, inability to maintain organization, very low self esteem, depression, and an impulse escape into stimulation. The OCD part has manifested in a past wrought with anorexia, dysmorphia, social anxiety, compulsive nail biting with skin picking and insomnia. Treatment has been very difficult as meds usually given for ADHD seem to trigger my OCD. I've tried many different drugs without the desired effects until I was prescribed Zoloft but developed a rash from my chest up. I quit taking it immediately. Before I quit taking it, there was a window of time in which I felt a lovely sense of well being foreign to me before and since. I have a friend who suffered extreme anxiety and had an allergic reaction (asthma) when he tried Zoloft as well. He liked the way it made him feel so much he decided to quit temporarily and then acclimate his body to it very slowly until he reached a full but low dosage over a period of months. I told my doctor I wanted to try this method and he responded, "Just take these Lexapro samples. It's not worth dying over! You have OCD and are obsessing on Zoloft." But I've taken Lexapro before and still had my compulsions. I'd love to go get a second and third opinion but have no insurance and can't afford it. I have not taken the Lexapro samples yet and have been considering buying Zoloft online or from my friend and trying this little experiment on my own. I know no Doctor would advise this but if I tried very low doses what is the likelihood that I could severely damage to my liver or otherwise? Could I really die? I would of course stop if I developed a rash again. After trying lexapro, busbar, imipramine, propranolol, conerta, ambien, xanax, lunesta, trazodone, prozac, abilify, welbutrin, ritalin, adderall, dexedrene, 5 years of $$$ therapy, exercise, fish oil, ginko, ginsing, 5htp, vit D, and ongoing positive reaffirmations I still feel like a frustrated, underachieving, obsessive mess. Not to mention my partners frustration in living with me. My question is, have you heard of anyone trying this with any success? What would you do? Have you heard of any other drugs for hybrid cases like mine? Thank you for your time and caring, Terry